Genotoxic Evaluation of a Methanolic Extract of Verbascum Thapsus using Micronucleus Test in Mouse Bone Marrow
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چکیده
منابع مشابه
Genotoxic, Cytotoxic, Antigenotoxic, and Anticytotoxic Effects of Sulfonamide Chalcone Using the Ames Test and the Mouse Bone Marrow Micronucleus Test
Chalcones present several biological activities and sulfonamide chalcone derivatives have shown important biological applications, including antitumor activity. In this study, genotoxic, cytotoxic, antigenotoxic, and anticytotoxic activities of the sulfonamide chalcone N-{4-[3-(4-nitrophenyl)prop-2-enoyl]phenyl} benzenesulfonamide (CPN) were assessed using the Salmonella typhimurium reverse mut...
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Ten halogenated aliphatic hydrocarbons (carbon tetrachloride, 1-chlorohexane, 2,3-dichlorobutane, 1,2-dichloroethane, 1,2-dichloroethylene, 1,3-dichloropropane, hexachloroethane, 1,1,2-trichloroethane, 1,2,3-trichloropropane and 1,1,3-trichloropropene), previously assayed in genetic assays in fungi, were evaluated in the mouse bone marrow micronucleus test in order to assess their genotoxicity ...
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The present study was designed to evaluate the antimutagenic potential of ripe Aegle marmelos fruit, using micronucleus and chromosomal aberration assay in mouse bone marrow. The antimutagenic effect of 50% methanolic extract of ripe Aegle marmelos fruit was assessed using cyclophosphamide induced micronuclei (MN) formation and chromosomal aberration (CA) in mouse. The animals were pre-treated ...
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Background & Aim: The World Health Organization (WHO) estimated that majority of the inhabitants of the world rely chiefly on folk medicine. It, therefore, approved the use of herbal products for national policies and drug regulatory measures in order to strengthen research and evaluation of the safety and efficacy of herbal products. We have evaluated the cytotoxic, mutagenic ...
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ژورنال
عنوان ژورنال: Natural Product Communications
سال: 2011
ISSN: 1934-578X,1555-9475
DOI: 10.1177/1934578x1100600716